Product Name: AZ 628
Synonyms: 3-(1-cyano-1-methylethyl)-N-[3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-methylphenyl]-benzamideWeb Site click
Product Overview: A quinazilinone that inhibits several Raf kinases, including B-Raf, B-RafV600E, and c-Raf-1 (IC50s = 105, 34, and 29 nM in vitro); inhibits anchorage-dependent and -independent growth, induces cell cycle arrest, and causes apoptosis in colon and melanoma
Shipping: wet ice
CAS NO: 0 XMU-MP-1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H25N5O2
SMILES: CC(C)(C#N)C1=CC=CC(C(NC2=CC(NC3=CC(C(N(C)C=N4)=O)=C4C=C3)=C(C)C=C2)=O)=C1HIV inhibitors
Molecular Weight: 451.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/1/418.abstract
