Product Name: AT-406
Synonyms: (5S,8S,10aR)-N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-pyrrolo[1,2-a][1,5]diazocine-8-carboxamide Web Site click
Product Overview: An orally bioavailable Smac/DIABLO mimetic and antagonist of IAPs (Kis = 66.4, 1.9, and 5.1 nM for XIAP, cIAP1, and cIAP2, respectively); inhibits cancer cell growth in various human cancer cell lines and induces apoptosis in xenograft tumors in miceAT-40
Shipping: wet ice
CAS NO: 1231929-97-7 Product: LY2835219 (free base)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C32H43N5O4
SMILES: O=C(NC(C1=CC=CC=C1)C2=CC=CC=C2)[C@H]3N4C([C@@H](NC([C@@H](NC)C)=O)CN(C(CC(C)C)=O)CC[C@@]4([H])CC3)=OStearoyl-CoA Desaturase SCD) inhibitors
Molecular Weight: 561.7
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/60/1/87.abstract
