Product Name: AMG 900
Synonyms: N-[4-[[3-(2-amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamineMedchemexpress.com
Product Overview: A selective Aurora kinase inhibitor (IC50s = 5, 4, and 1 nM for Aurora A, B, and C, respectively); inhibits the proliferation of 26 different tumor cell lines in vitro and is broadly active in multiple xenograft modelsThree Aurora kinases, A-C, are involv
Shipping: wet ice
CAS NO: 1401963-17-4 Product: Vc-MMAD
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H21N7OS
SMILES: NC1=NC=CC(C2=C(OC3=CC=C(NC4=C(C=CC=C5)C5=C(C6=CC(C)=CS6)N=N4)C=C3)N=CC=C2)=N1Neuronal Signaling inhibitors
Molecular Weight: 503.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/9/5220.abstract
Related Posts
Product Name: AMG-900
Synonyms: Web Site：Medchemexpress
Product Overview: AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
Shipping: wet ice
CAS NO: 136-40-3 Product: Phenazopyridine (hydrochloride)
Stability: Store at +4 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H21N7OS
SMILES: Isocitrate Dehydrogenase (IDH) inhibitors
Molecular Weight: 503.58
Formulation: solution 10mM in DMSO
Purity: 0.98PubMed ID:http://aac.asm.org/content/46/7/2244.abstract