Product Name: AMG 319
Synonyms: 7-fluoro-αS-methyl-N-9H-purin-6-yl-2-(2-pyridinyl)-3-quinolinemethanamineWeb Site click
Product Overview: A potent, selective inhibitor of PI3Kδ (IC50 = 18 nM); blocks anti-IgM/CD40L-induced proliferation (IC50 = 8.6 nM) and reduces Akt phosphorylation (IC50 = 1.5 nM) in B cells; reduces inflammation in two animal modelsAMG 319 is a potent inhibitor of
Shipping: dry ice
CAS NO: 784210-87-3 Product: RGB-286638
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H16FN7
SMILES: C[C@@H](C1=CC(C=CC(F)=C2)=C2N=C1C3=CC=CC=N3)NC4=C5C(N=CN5)=NC=N4Prostaglandin Receptor inhibitors
Molecular Weight: 385.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/48/1/137.abstract
