Product Name: ALK-IN-1
Synonyms: 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamineWeb Site click
Product Overview: A potent inhibitor of ALK (IC50 = 0.07 nM) that is less effective at IGF-1R and InsR (IC50s = 3.2 and 100 nM, respectively); drives cell death in (ALK+) Karpas-299 lymphoma cells with an IC50 value of 41.5 nM, while killing (ALK-) U937 cells with an IC50
Shipping: wet ice
CAS NO: 105826-92-4 Product: Tropisetron (Hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H34ClN6O2P
SMILES: CN(C)C1CCN(C2=CC(OC)=C(NC3=NC=C(Cl)C(NC4=CC=CC=C4P(C)(C)=O)=N3)C=C2)CC1TGF-beta_Smad inhibitors
Molecular Weight: 529
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/6/3355.abstract
