Product Name: A-77-01
Synonyms: 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinolineMedchemexpress
Product Overview: A potent inhibitor of the TGF-β1 receptor ALK5 (IC550 = 25 nM), blocking SMAD2 phosphorylation and growth inhibitory effects of TGF-β; prevents EMT transition in NMuMG cells treated with TGF-βA-77-01 is a potent inhibitor of the TGF-β1
Shipping: wet ice
CAS NO: 846589-98-8 Product: Lorcaserin (Hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H14N4
SMILES: CC1=NC(C2=NNC=C2C3=CC=NC4=C3C=CC=C4)=CC=C1TGF-beta) Receptor inhibitors
Molecular Weight: 286.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/6/3480.abstract
