Product Name: 3-Deazaneplanocin A
Synonyms: 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol DZNep Web Site：Medchemexpress
Product Overview: An inhibitor of SAH hydrolase; depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in acute myeloid leukemia cells in a dose-dependent manner (0.2-1 μM); increases expression of the cell-cycle regulators p21, p27, and FBXO32 lea
Shipping: wet ice
CAS NO: 1133432-49-1 GDC-0834
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C12H14N4O3
SMILES: NC1=NC=CC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)C(CC)=C3Aldehyde Dehydrogenase ALDH) inhibitors
Molecular Weight: 262.3
Formulation: A crystalline solid
Purity: ≥97%PubMed ID:http://www.bloodjournal.org/content/127/5/529
