Heme “mentorspecialist in trainingpatient” due to limited time,so there is a necessarity to place cheap and offered for clinicians ultrasound simulators into trainingpractice. Aims Solutions: The aim was to make the experimental model of Doppler ultrasound simulation program which will be able to imitate arterial and venous blood flow and focal lesions of parenchymal organs with many form of vascularization for the gastroenterologists ultrasound education. Material and techniques: Vascular phantom was created in our Dilemma scientific investigation Laboratory “Diagnostic researches and miniinvasive technologies” in . It represents tube method and consists of two components. The st element is vascular with imitative qualities of arterial and venous blood flow (together with the opportunity of laminar and turbulent flow PHCCC biological activity recreation,making use of semiautomatic dispenser). The nd element is “pathological foci”,it represents hemodynamics of capillary and cavernous hemangioma,focal nodular hyperplasia and hypervascular liver metastases. There have been groups of year health-related students of Smolensk State Health-related University with in every group for the Phantom’s efficiency testing. Educational approach in the st group was by the normal scheme “mentorstudentpatient” ( instances). Educational approach within the nd group consisted of stages: at the st stage all of the students had practice using the ultrasound simulator and at the nd stage there was regular scheme “mentorstudentpatient” ( times). Benefits: After weeks of instruction all the students have been tested in real work with patients with arterial blood flow pathology (aneurysm,n),venous blood flow pathology (cavernous portal vein transformation at cirrhosis n,capillary and cavernous hemangioma,n,focal nodular liver hyperplasia n,colorectal liver metastases,n). In the st group truepositive final results amounted . ,falsepositive benefits . ,falsenegative benefits . . Within the nd group truepositive results amounted . ,falsepositive results . ,falsenegative final results . . Conclusion: Phantom’s use at the st stage of gastroenterologists education in ultrasound technique qualitatively improved the efficiency of healthcare specialists’ work,so it demands overall introduction of simulatortraining in courses of postgraduate qualified education. Disclosure PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26212255 of Interest: None declaredA P GASTROINTESTINAL NEUROENDOCRINE TUMORS UNKNOWN Main Web-site: REPORT FROM A SERIES AT A SINGLE INSTITUTE S. Massironi,I. Fanetti,,F. Cavalcoli,,A. Zilli,,D. Conte,Gastroenterology and Endoscopic Unit,Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico ,Division of Pathophysiology and Transplantation,Universita` degli Studi di Milano,Milano,Italy Get in touch with E mail Address: cavalcoli.federicagmail Introduction: Neuroendocrine neoplasms (NENs),a heterogeneous group of neoplasms,differ in biologic behavior,histologic appearance and response to remedy. NENs with unknown primary internet site (NENsUP) account for to percent of all NENs. Aims Techniques: We here describe clinical findings,histologic and anatomic traits as well as the diagnostic workup of sufferers with histologically confirmed metastatic NENs of unknown principal. Amongst January to January ,on the sufferers with metastatic gastrointestinal NENs seen at our Institution,( (M:F :; median age at the diagnosis years,variety ) presented with immunohistochemically verified neuroendocrine metastases devoid of evidence of primary web-site in spite of an exhaustive workup based on computed tomography (CT),magnetic resonance (M.