At min of . versus . . at baseline in addition to a imply dosecumulative at min of . . versus . at baseline. Similarly,throughout rabeprazole therapy,the mean doseh at min was . . versus . . at baseline and also the imply dosecumulative at min was . . versus . . at baseline. Conclusion: No differences is detectable involving pantoprazole and rabeprazole use in individuals with HCVrelated liver cirrhosis. Pantoprazole do not considerably impair the CYP pathway activity in these sufferers. Both PPIs are safe for therapy of sufferers with advanced liver disease. References . Giannini E,Romagnoli P,Fasoli A. Influence of Helicobacter pylori eradication therapy on Caminopyrine breath test: comparison among omeoprazole,lansoprazole,or pantoprazolecontaining regimens. Am J Gastroenterol. . McColl KEL,Kennerley P. Proton Pump Inhibitors: variations emerge in hepatic metabolism. Dig Liver Dis. Disclosure of Interest: None declaredP SPONTANEOUS BACTERIAL PERITONITIS IN Individuals WITH CIRRHOSIS AND ASCITES ITS PREVALENCE,CLINICAL AND PARACLINICAL Options D. Matei,,A. David,N. Al Hajjar,,I. Groza,R. Prundus,V. Andreica,,M. Tantau,University of Medicine and Pharmacy Iuliu Hatieganu,Regional Institute of Gastroenterology and Hepatology ,Cluj get Talarozole (R enantiomer) Napoca,Romania Introduction: Spontaneous bacterial peritonitis (SBP) is usually a serious complication occurring in patients with liver cirrhosis and ascites and it really is associated with a higher mortality rate. Aims Strategies: The aim of this study would be to evaluate the prevalence on the SBP in hospitalised individuals with cirrhosis and ascites and also their clinical and paraclinical traits. Components and procedures. This crosssectional study enrolled all sufferers diagnosed with liver cirrhosis and ascites ,who have been hospitalised in a tertiary healthcare center more than a period of months (January June. The diagnosis for SBP consists of polymorphonuclear (PMN) counts ! cells mm andor a optimistic ascitic fluid culture,without the need of any evidence of external or intraabdominal infectious source. To evaluate our sufferers,who have been divided in two groups (SBP and nonSBP),we compared the following data: age,gender,etiology of cirrhosis,volume of ascitic fluid,hypotension,tachycardia,hepatic encephalopathy,upper gastrointestinal bleeding,hepatorenal syndrome,hepatocellular carcinoma,hepatic PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26212255 hydrothorax,leukocytosis and MELD Score (Model of Endstage Liver Illness). Benefits: patients with cirrhosis and ascites have been integrated in our study. The imply age was . years (min years,max years) and there was a male predominance ( . with the individuals had SBP. By comparing the SBP along with the nonSBP patients,the following substantial differences were discovered: male gender . vs . (p.); voluminous ascites . vs . (p); hepatic encephalopathy . vs (p); hepatorenal syndrome . vs . (p); hepatic hydrothorax . vs . (p.); leukocytosis . vs (p.) and also the MELD Score ! points . vs . (p). Employing multivariate evaluation,4 out of those factors had been identified as being independent things substantially connected with SBP: voluminous ascites (OR CI:. p),hepatic encephalopathy (OR CI:. p.),hepatorenal syndrome (HR CI:. p.) plus the MELD Score ! points (HR CI:. p.).United European Gastroenterology Journal (S) P MANAGEMENT NATIONAL SURVEY OF GASTRIC VARICES: A FRENCHA Final results: On admission. of individuals (n) had a CLIF SOFA and only . (n) had a CLIFSOFA . Amongst each of the obtainable prognostic scores,the ideal predictor of inICU mortality was a CLIFSOFA ! (OR, CI : ., p, PPV.),followed by a SOFA (OR, CI: ., p , P.