**Background** Anxiety and depression are prevalent psychiatric disorders that significantly impact global health and quality of life. These conditions are often associated with imbalances in neurotransmitter systems, particularly the serotonergic…
Periodontitis is a chronic inflammatory condition characterized by progressive destruction of the alveolar bone and periodontal ligament, leading to tooth mobility and loss. Despite advances in mechanical debridement, conventional treatments…
Protein vesicles have emerged as a transformative platform in nanomedicine, offering a unique combination of biocompatibility, structural stability, and genetic programmability. In this study, we present a highly advanced, genetically…
The ability of dynamic polymer networks (DPNs) to self-repair and reconfigure at interfaces is a defining feature of vitrimer-based materials. In this study, the interfacial healing behavior between amine-terminated polystyrene…
Isothermal titration calorimetry (ITC) extends far beyond simple 1:1 binding studies, offering powerful insights into complex biological interactions that govern cellular function and disease mechanisms. Its ability to provide a…
Racemases and epimerases operating through a 1,1-proton transfer mechanism represent a unique class of enzymes with profound implications in metabolism, disease, and biotechnology. Their ability to interconvert enantiomers at chiral…