Name :
LGALS1 Protein
Description :
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties.
Species :
Human
Uniprotkb :
E. coli
Tag :
C-6His
Synonyms :
HPL, S-Lac Lectin 1, Lactose-Binding Lectin 1, 14 kDa Lectin, Beta-Galactoside-Binding Lectin L-14-I, Gal-1, HBL, Lectin Galactoside-Binding Soluble 1, Galectin-1, Putative MAPK-Activating Protein PM12, Galaptin, LG, HLBP14, 14 kDa Laminin-Binding Protein, β-Galactoside-Binding Lectin L-14-I
Construction :
Recombinant Human Galectin-1 is produced by our E.coli expression system and the target gene encoding Ala2-Asp135 is expressed with a 6His tag at the C-terminus.
Protein Purity :
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight :
15 KDa, reducing conditions
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulatione :
Lyophilized from a 0.2 μm filtered solution of 20mM Citrate, 8% Trehalose, 4% Mannitol, 50mM NaCl, 1mM TCEP, 0.05% Tween 80, pH 4.0.
Reconstitution :
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Stability & Storage :
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping :
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Research Background :
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties.
References and Literature :
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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