VU0483605
VU0483605

VU0483605

Product Name: VU0483605
Synonyms: 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamideMedchemexpress.com
Product Overview: A selective mGluR1 PAM (EC50s = 0.39 and 0.36 μM for human and rat receptors, respectively) with no activity as a mGlu4 PAM (EC50 >10 μM); potentiates a response to glutamate in wild-type cell lines stably expressing mGlu1 and partially restores
Shipping: wet ice
CAS NO: 198474-05-4 Product: PF-06840003
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H10Cl3N3O3
SMILES: O=C1N(C2=CC=C(NC(C3=C(Cl)C=CC=N3)=O)C=C2Cl)C(C4=CC=CC(Cl)=C41)=OCNS-penetrant_Compound_Library inhibitors
Molecular Weight: 446.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/12/5146.abstract