Product Name: Purvalanol A
Synonyms: (2R)-2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol NG 60Web Site click
Product Overview: A potent, cell-permeable, and selective inhibitor of CDKs (IC50s = 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively); reversibly arrests synchronized cells in the G1 and G2 phase of the c
Shipping: wet ice
CAS NO: 461054-93-3 Ko 143
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H25ClN6O
SMILES: CC(C)N1C2=NC(N[C@H](C(C)C)CO)=NC(NC3=CC(Cl)=CC=C3)=C2N=C1Protein Tyrosine Kinase_RTK inhibitors
Molecular Weight: 388.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/1/5
