PLX4720
PLX4720

PLX4720

Product Name: PLX4720
Synonyms: N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide Raf Kinase Inhibitor VWeb Site click
Product Overview: An orally-available, highly selective inhibitor of B-RafV600E (IC50 = 13 nM); less effective against wild type B-Raf (IC50 = 160 nM) as well as several other kinases; induces cell cycle arrest and apoptosis in cells and xenografts expressing the mutant of
Shipping: wet ice
CAS NO: 1012054-59-9 CUDC-101
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H14ClF2N3O3S
SMILES: O=C(C1=C(F)C(NS(CCC)(=O)=O)=CC=C1F)C2=CNC3=NC=C(Cl)C=C32Dopamine Receptor inhibitors
Molecular Weight: 413.8
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/54/9/3678.abstract