I-BET762
I-BET762

I-BET762

Product Name: I-BET762
Synonyms: (S)-2-(6-(4-chlorophenyl)-8-methoxy-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-N-ethylacetamide GSK525762AMedchemexpress.com
Product Overview: A synthetic compound which interacts with BET proteins with high-affinity (Kd = 32.5-42.5 nM); disrupts binding of BET proteins with acetylated histones, suppressing the expression of specific inflammatory genes involved in sepsis and endotoxic shockThe b
Shipping: wet ice
CAS NO: 76822-21-4 Product: Danshensu
Stability: Store at -20 degrees; shelf life 365 days maximum after production
Molecular Formula: C22H22ClN5O2
SMILES: COC1=CC(C(C2=CC=C(Cl)C=C2)=N[[email protected]]3CC(N(CC)[H])=O)=C(N4C3=NN=C4C)C=C1JAK_STAT Signaling inhibitors
Molecular Weight: 423.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/8/3944.abstract