Everolimus
Everolimus

Everolimus

Product Name: Everolimus
Synonyms: 42-O-(2-hydroxyethyl)-rapamycin Afinitor® Web Site:Medchemexpress
Product Overview: A hydroxyethyl ether rapamycin derivative that inhibits mTOR signaling through both mTORC1 and mTORC2 when added to cells at 20 nM; orally available with superior pharmacokinetics and pharmacodynamics over rapamycinThe mammalian target of rapamycin (mTOR)
Shipping: wet ice
CAS NO: 379231-04-6 Saracatinib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C53H83NO14
SMILES: O=C([[email protected]]1([H])CCCCN1C(C([[email protected]@]2(O)[[email protected]](C)CC[[email protected]](C[[email protected]](OC)/C(C)=C/C=C/C=C/[[email protected]](C3)C)([H])O2)=O)=O)O[[email protected]](CC([[email protected]](C)/C=C(C)/[[email protected]@H](O)[[email protected]@H](OC)C([[email protected]@H]3C)=O)=O)([H])[[email protected]](C)C[[email protected]]4C[[email protected]@H](OC)[[email protected]](OCCO)CC4Hedgehog inhibitors
Molecular Weight: 958.2
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/9/1065