E-4031 (hydrochloride)

Product Name: E-4031 (hydrochloride)
Synonyms: N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-methanesulfonamide, dihydrochlorideMedchemexpress.com
Product Overview: A methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM); inhibits the ERG1, ERG2, and ERG3 isoforms with KD values of 99, 116, and 193 nM, respectivelyVoltage-gated p
Shipping: wet ice
CAS NO: 1232416-25-9 VE-822
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H27N3O3S • 2HCl
SMILES: O=C(C1CCN(CCC2=CC=CC(C)=N2)CC1)C3=CC=C(NS(C)(=O)=O)C=C3.Cl.ClLXR inhibitors
Molecular Weight: 474.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/4/487